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- Synthesis of Peptide Nucleic Acids (PNA)Peptide nucleic acid (PNA) synthesis is the process of creating PNA oligomers in the laboratory. The synthesis of peptide nucleic acid is a synthetic nucleic acid analogue that has a pseudopeptide backbone, making it resistant to enzymatic degradation and stable under a wide range of conditions. The synthesis of PNA involves solid-phase synthesis techniques, where each nucleotide monomer is...0 Comments 0 SharesPlease log in to like, share and comment!
- Application of PeptidesDiscovery and Structure Calcitonin, also called thyrocalcitonin, a protein hormone synthesized and secreted in humans and other mammals primarily by parafollicular cells (C cell) in the thyroid gland. At first it was believed that this hypocalcemic agent was produced by the parathyroid glands. Shortly thereafter, however, it was demonstrated that calcitonin was produced specifically...0 Comments 0 Shares
- Introduction to PNA Nucleobase ModificationsStructure and Properties of PNA Peptide nucleic acids (PNAs) are sophisticated oligonucleotide analogs that feature nucleobases, a peptide backbone, as well as an N-terminus and a C-terminus. The nucleobases embedded in PNAs are the classic adenine (A), guanine (G), cytosine (C), and thymine (T), all of which can also be found in DNA. However, the nucleobases in PNAs are not attached to the...0 Comments 0 Shares
- How to Design Cell Penetrating Peptides?Applications and chemical structural features of cell-penetrating peptides Cell-penetrating peptides are a class of short peptides with a length of 5~30 amino acids, which can carry peptides, nucleic acids, small molecules of drugs, and virus particles through cell membranes into cells. People use it as a carrier to transport objects into cells. Past research has proven effective in...0 Comments 0 Shares
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