Introduction to PNA Nucleobase Modifications
Structure and Properties of PNA
Peptide nucleic acids (PNAs) are sophisticated oligonucleotide analogs that feature nucleobases, a peptide backbone, as well as an N-terminus and a C-terminus. The nucleobases embedded in PNAs are the classic adenine (A), guanine (G), cytosine (C), and thymine (T), all of which can also be found in DNA. However, the nucleobases in PNAs are not attached to the...
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